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A randomised preclinical trial of adrenaline use during cardiac arrest in mice

BACKGROUND: Adrenaline is routinely administered during cardiac arrest resuscitation. Using a novel murine model of cardiac arrest, this study evaluates the effects of adrenaline use on survival and end-organ injury. METHODS: A total of 58 mice, including cardiac arrest (CA) and sham (SHAM) groups r...

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Detalles Bibliográficos
Autores principales: Donner, Daniel G., Bloom, Jason E., Shihata, Waled A., Brown, Aascha A., Cook, Rosalind, Yee Tai, Tsin, Lambert, Gavin W., Chu, Po-Yin, Chan, William, Stub, Dion, Wang, Bing H., Kaye, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436797/
https://www.ncbi.nlm.nih.gov/pubmed/36059384
http://dx.doi.org/10.1016/j.resplu.2022.100292