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A short amphipathic alpha helix in scavenger receptor BI facilitates bidirectional HDL-cholesterol transport

During reverse cholesterol transport, high-density lipoprotein (HDL) carries excess cholesterol from peripheral cells to the liver for excretion in bile. The first and last steps of this pathway involve the HDL receptor, scavenger receptor BI (SR-BI). While the mechanism of SR-BI-mediated cholestero...

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Detalles Bibliográficos
Autores principales: May, Sarah C., Sahoo, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436806/
https://www.ncbi.nlm.nih.gov/pubmed/35926711
http://dx.doi.org/10.1016/j.jbc.2022.102333