Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury

Ischemia-reperfusion (I/R) injury is a promising therapeutic target to improve clinical outcomes after acute myocardial infarction. Ferroptosis, triggered by iron overload and excessive lipid peroxides, is reportedly involved in I/R injury. However, its significance and mechanistic basis remain uncl...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyamoto, Hiroko Deguchi, Ikeda, Masataka, Ide, Tomomi, Tadokoro, Tomonori, Furusawa, Shun, Abe, Ko, Ishimaru, Kosei, Enzan, Nobuyuki, Sada, Masashi, Yamamoto, Taishi, Matsushima, Shouji, Koumura, Tomoko, Yamada, Ken-ichi, Imai, Hirotaka, Tsutsui, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436815/
https://www.ncbi.nlm.nih.gov/pubmed/36061338
http://dx.doi.org/10.1016/j.jacbts.2022.03.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436815/
https://www.ncbi.nlm.nih.gov/pubmed/36061338
http://dx.doi.org/10.1016/j.jacbts.2022.03.012

Ejemplares similares