EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association

Epidermal growth factor (EGF) is one of the most well-characterized growth factors and plays a crucial role in cell proliferation and differentiation. Its receptor EGFR has been extensively explored as a therapeutic target against multiple types of cancers, such as lung cancer and glioblastoma. Rece...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yang, Shu, Hengyao, Liu, Jia, Jin, Xin, Wang, Lihua, Qu, Yanzhao, Xia, Mingjie, Peng, Pinghui, Feng, Yunpeng, Wei, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436816/
https://www.ncbi.nlm.nih.gov/pubmed/35931120
http://dx.doi.org/10.1016/j.jbc.2022.102340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436816/
https://www.ncbi.nlm.nih.gov/pubmed/35931120
http://dx.doi.org/10.1016/j.jbc.2022.102340

Ejemplares similares