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EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association
Epidermal growth factor (EGF) is one of the most well-characterized growth factors and plays a crucial role in cell proliferation and differentiation. Its receptor EGFR has been extensively explored as a therapeutic target against multiple types of cancers, such as lung cancer and glioblastoma. Rece...
Autores principales: | Wang, Yang, Shu, Hengyao, Liu, Jia, Jin, Xin, Wang, Lihua, Qu, Yanzhao, Xia, Mingjie, Peng, Pinghui, Feng, Yunpeng, Wei, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436816/ https://www.ncbi.nlm.nih.gov/pubmed/35931120 http://dx.doi.org/10.1016/j.jbc.2022.102340 |
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