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The PI3K/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities

OBJECTS: Traumatic spinal cord injury (TSCI) causes neurological dysfunction below the injured segment of the spinal cord, which significantly impacts the quality of life in affected patients. The phosphoinositide 3kinase/serine‐threonine kinase (PI3K/AKT) signaling pathway offers a potential therap...

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Detalles Bibliográficos
Autores principales: He, Xuegang, Li, Ying, Deng, Bo, Lin, Aixin, Zhang, Guangzhi, Ma, Miao, Wang, Yonggang, Yang, Yong, Kang, Xuewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436900/
https://www.ncbi.nlm.nih.gov/pubmed/35754255
http://dx.doi.org/10.1111/cpr.13275