Cargando…

Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway

BACKGROUND: Mesangial cell proliferation is the most basic pathological feature of immunoglobulin A nephropathy (IgAN); however, the specific underlying mechanism and an appropriate therapeutic strategy are yet to be unearthed. This study aimed to investigate the therapeutic effect of triptolide (TP...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Lu, Lan, Zhixin, Peng, Liang, Wan, Lili, Liu, Di, Tan, Xia, Tang, Chengyuan, Chen, Guochun, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436901/
https://www.ncbi.nlm.nih.gov/pubmed/35733381
http://dx.doi.org/10.1111/cpr.13278