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CD33‐targeting extracellular vesicles deliver antisense oligonucleotides against FLT3‐ITD and miR‐125b for specific treatment of acute myeloid leukaemia

INTRODUCTION: Acute Myeloid Leukaemia (AML) is the most common blood cancer in adults. Although 2 out of 3 AML patients go into total remission after chemotherapies and targeted therapies, the disease recurs in 60%–65% of younger adult patients within 3 years after diagnosis with a dramatically decr...

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Detalles Bibliográficos
Autores principales: Chen, Huan, Jayasinghe, Migara Kavishka, Yeo, Eric Yew Meng, Wu, Zhiyuan, Pirisinu, Marco, Usman, Waqas Muhammad, Pham, Thach Tuan, Lim, Kah Wai, Tran, Nhan Van, Leung, Anskar Y. H., Du, Xin, Zhang, Qiaoxia, Phan, Anh Tuân, Le, Minh T. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436904/
https://www.ncbi.nlm.nih.gov/pubmed/35851970
http://dx.doi.org/10.1111/cpr.13255