Opposite roles of Kindlin orthologs in cell survival and proliferation

OBJECTIVE: It is unclear why adhesion‐dependent cells such as epithelium undergo anoikis without anchorage, while adhesion‐independent blood cells thrive in suspension. The adhesive machinery of these cells is similar, with the exception of Kindlin orthologs, Kindlin 2 (K2) and Kindlin 3 (K3). Here...

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Detalles Bibliográficos
Autores principales: Zhevlakova, Irina, Xiong, Luyang, Liu, Huan, Dudiki, Tejasvi, Ciocea, Alieta, Podrez, Eugene, Byzova, Tatiana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436913/
https://www.ncbi.nlm.nih.gov/pubmed/35860876
http://dx.doi.org/10.1111/cpr.13280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436913/
https://www.ncbi.nlm.nih.gov/pubmed/35860876
http://dx.doi.org/10.1111/cpr.13280

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