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Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer

Granule neurons are the most common cell type in the cerebellum. They are generated in the external granule layer and migrate inwardly, forming the internal granule layer. Small Rho GTPases play various roles during development of the nervous system and may be involved in generation, differentiation...

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Detalles Bibliográficos
Autores principales: Katayama, Kei-ichi, Zheng, Yi, Inoue, Norimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436960/
https://www.ncbi.nlm.nih.gov/pubmed/36050459
http://dx.doi.org/10.1038/s41598-022-19252-y