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Dietary 7-ketocholesterol exacerbates myocardial ischemia–reperfusion injury in mice through monocyte/macrophage-mediated inflammation
Emerging evidence suggests that 7-ketocholesterol (7-KC), one of the most abundant dietary oxysterols, causes inflammation and cardiovascular diseases. Here we show the deteriorating effects of dietary 7-KC on myocardial ischemia–reperfusion (IR) injury and detailed the molecular mechanisms. A high-...
Autores principales: | Uchikawa, Tomoki, Matoba, Tetsuya, Kawahara, Takuro, Baba, Isashi, Katsuki, Shunsuke, Koga, Jun-ichiro, Hashimoto, Yu, Yamasaki, Ryo, Ichi, Ikuyo, Akita, Hidetaka, Tsutsui, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436973/ https://www.ncbi.nlm.nih.gov/pubmed/36050346 http://dx.doi.org/10.1038/s41598-022-19065-z |
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