Percolation transition prescribes protein size-specific barrier to passive transport through the nuclear pore complex

Nuclear pore complexes (NPCs) control biomolecular transport in and out of the nucleus. Disordered nucleoporins in the complex’s pore form a permeation barrier, preventing unassisted transport of large biomolecules. Here, we combine coarse-grained simulations of experimentally derived NPC structures...

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Detalles Bibliográficos
Autores principales: Winogradoff, David, Chou, Han-Yi, Maffeo, Christopher, Aksimentiev, Aleksei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437005/
https://www.ncbi.nlm.nih.gov/pubmed/36050301
http://dx.doi.org/10.1038/s41467-022-32857-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437005/
https://www.ncbi.nlm.nih.gov/pubmed/36050301
http://dx.doi.org/10.1038/s41467-022-32857-1

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