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Percolation transition prescribes protein size-specific barrier to passive transport through the nuclear pore complex
Nuclear pore complexes (NPCs) control biomolecular transport in and out of the nucleus. Disordered nucleoporins in the complex’s pore form a permeation barrier, preventing unassisted transport of large biomolecules. Here, we combine coarse-grained simulations of experimentally derived NPC structures...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437005/ https://www.ncbi.nlm.nih.gov/pubmed/36050301 http://dx.doi.org/10.1038/s41467-022-32857-1 |