Frequency of functional exonic single-nucleotide polymorphisms and haplotype distribution in the SLCO1B1 gene across genetic ancestry groups in the Qatari population

Organic anion transporting polypeptides (OATP), which are encoded by SLCO genes, participate in the hepatic elimination of drugs and xenobiotics. SLCO1B1 is an important pharmacogenomic gene (encoding OATP1B1) associated with response to the uptake of endogenous compounds, such as statin and bilirub...

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Detalles Bibliográficos
Autores principales: Dashti, Mohammed, Al-Matrouk, Abdullah, Channanath, Arshad, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437070/
https://www.ncbi.nlm.nih.gov/pubmed/36050458
http://dx.doi.org/10.1038/s41598-022-19318-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437070/
https://www.ncbi.nlm.nih.gov/pubmed/36050458
http://dx.doi.org/10.1038/s41598-022-19318-x

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