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Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis

Glioblastoma (GBM) is the most aggressive primary brain tumour for which both effective treatments and efficient tools for an early-stage diagnosis are lacking. Herein, we present curcumin-based fluorescent probes that are able to bind to aldehyde dehydrogenase 1A3 (ALDH1A3), an enzyme overexpressed...

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Detalles Bibliográficos
Autores principales: Gelardi, Edoardo L. M., Caprioglio, Diego, Colombo, Giorgia, Del Grosso, Erika, Mazzoletti, Daniele, Mattoteia, Daiana, Salamone, Stefano, Ferraris, Davide M., Aronica, Eleonora, Nato, Giulia, Buffo, Annalisa, Rizzi, Menico, Magrassi, Lorenzo, Minassi, Alberto, Garavaglia, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437101/
https://www.ncbi.nlm.nih.gov/pubmed/36050388
http://dx.doi.org/10.1038/s42003-022-03834-7