Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis

Epstein–Barr virus (EBV) infection precedes multiple sclerosis (MS) pathology and cross-reactive antibodies might link EBV infection to CNS autoimmunity. As an altered anti-EBV T cell reaction was suggested in MS, we queried peripheral blood T cell receptor β chain (TCRβ) repertoires of 1,395 MS pat...

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Detalles Bibliográficos
Autores principales: Schneider-Hohendorf, Tilman, Gerdes, Lisa Ann, Pignolet, Béatrice, Gittelman, Rachel, Ostkamp, Patrick, Rubelt, Florian, Raposo, Catarina, Tackenberg, Björn, Riepenhausen, Marianne, Janoschka, Claudia, Wünsch, Christian, Bucciarelli, Florence, Flierl-Hecht, Andrea, Beltrán, Eduardo, Kümpfel, Tania, Anslinger, Katja, Gross, Catharina C., Chapman, Heidi, Kaplan, Ian, Brassat, David, Wekerle, Hartmut, Kerschensteiner, Martin, Klotz, Luisa, Lünemann, Jan D., Hohlfeld, Reinhard, Liblau, Roland, Wiendl, Heinz, Schwab, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437111/
https://www.ncbi.nlm.nih.gov/pubmed/36048016
http://dx.doi.org/10.1084/jem.20220650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437111/
https://www.ncbi.nlm.nih.gov/pubmed/36048016
http://dx.doi.org/10.1084/jem.20220650

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