Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics

Lysosomes are highly dynamic organelles implicated in multiple diseases. Using live super-resolution microscopy, we found that lysosomal tethering events rarely undergo lysosomal fusion, but rather untether over time to reorganize the lysosomal network. Inter-lysosomal untethering events are driven...

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Detalles Bibliográficos
Autores principales: Wong, Yvette C., Kim, Soojin, Cisneros, Jasmine, Molakal, Catherine G., Song, Pingping, Lubbe, Steven J., Krainc, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437119/
https://www.ncbi.nlm.nih.gov/pubmed/36044022
http://dx.doi.org/10.1083/jcb.202206140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437119/
https://www.ncbi.nlm.nih.gov/pubmed/36044022
http://dx.doi.org/10.1083/jcb.202206140

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