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Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics
Lysosomes are highly dynamic organelles implicated in multiple diseases. Using live super-resolution microscopy, we found that lysosomal tethering events rarely undergo lysosomal fusion, but rather untether over time to reorganize the lysosomal network. Inter-lysosomal untethering events are driven...
Autores principales: | Wong, Yvette C., Kim, Soojin, Cisneros, Jasmine, Molakal, Catherine G., Song, Pingping, Lubbe, Steven J., Krainc, Dimitri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437119/ https://www.ncbi.nlm.nih.gov/pubmed/36044022 http://dx.doi.org/10.1083/jcb.202206140 |
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