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Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis

OBJECTIVE: Evaluating the efficacy of 3,6’‐dithioPomalidomide in 5xFAD Alzheimer's disease (AD) mice to test the hypothesis that neuroinflammation is directly involved in the development of synaptic/neuronal loss and cognitive decline. BACKGROUND: Amyloid‐β (Aβ) or tau‐focused clinical trials h...

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Detalles Bibliográficos
Autores principales: Lecca, Daniela, Jung, Yoo Jin, Scerba, Michael T., Hwang, Inho, Kim, Yu Kyung, Kim, Sun, Modrow, Sydney, Tweedie, David, Hsueh, Shih‐Chang, Liu, Dong, Luo, Weiming, Glotfelty, Elliot, Li, Yazhou, Wang, Jia‐Yi, Luo, Yu, Hoffer, Barry J., Kim, Dong Seok, McDevitt, Ross A., Greig, Nigel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437140/
https://www.ncbi.nlm.nih.gov/pubmed/35234334
http://dx.doi.org/10.1002/alz.12610