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Pharmacokinetics of the Port Delivery System with Ranibizumab in the Ladder Phase 2 Trial for Neovascular Age-Related Macular Degeneration

INTRODUCTION: Ladder was a phase 2 trial that evaluated the Port Delivery System with ranibizumab (PDS) for neovascular age-related macular degeneration. Serum and aqueous humor samples were collected to characterize the pharmacokinetics (PK) of ranibizumab delivered through the PDS. METHODS: Ladder...

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Detalles Bibliográficos
Autores principales: Wykoff, Charles C., Campochiaro, Peter A., Pieramici, Dante J., Khanani, Arshad M., Gune, Shamika, Maia, Mauricio, Kågedal, Matts, Ding, Han Ting, Maass, Katie F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437184/
https://www.ncbi.nlm.nih.gov/pubmed/35759124
http://dx.doi.org/10.1007/s40123-022-00532-9