Transcriptome changes in DM1 patients’ tissues are governed by the RNA interference pathway

Myotonic dystrophy type 1 (DM1) is a multisystemic disease caused by pathogenic expansions of CTG repeats. The expanded repeats are transcribed to long RNA and induce cellular toxicity. Recent studies suggest that the CUG repeats are processed by the RNA interference (RNAi) pathway to generate small...

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Detalles Bibliográficos
Autores principales: Braun, Maya, Shoshani, Shachar, Tabach, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437208/
https://www.ncbi.nlm.nih.gov/pubmed/36060259
http://dx.doi.org/10.3389/fmolb.2022.955753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437208/
https://www.ncbi.nlm.nih.gov/pubmed/36060259
http://dx.doi.org/10.3389/fmolb.2022.955753

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