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Age-dependent accumulation of tau aggregation in Caenorhabditis elegans

Aging is the primary risk factor for Alzheimer’s disease (AD) and related disorders (ADRDs). Tau aggregation is a hallmark of AD and other tauopathies. Even in normal aging, tau aggregation is found in brains, but in disease states, significantly more aggregated tau is present in brain regions demon...

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Detalles Bibliográficos
Autores principales: Aquino Nunez, Wendy, Combs, Benjamin, Gamblin, T. Chris, Ackley, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437221/
https://www.ncbi.nlm.nih.gov/pubmed/36062211
http://dx.doi.org/10.3389/fragi.2022.928574