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The intriguing dose-dependent effect of selected amphiphilic compounds on insulin amyloid aggregation: Focus on a cholesterol-based detergent, Chobimalt

The amyloidogenic self-assembly of many peptides and proteins largely depends on external conditions. Among amyloid-prone proteins, insulin attracts attention because of its physiological and therapeutic importance. In the present work, the amyloid aggregation of insulin is studied in the presence o...

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Detalles Bibliográficos
Autores principales: Siposova, Katarina, Petrenko, Viktor I., Garcarova, Ivana, Sedlakova, Dagmar, Almásy, László, Kyzyma, Olena A., Kriechbaum, Manfred, Musatov, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437268/
https://www.ncbi.nlm.nih.gov/pubmed/36060240
http://dx.doi.org/10.3389/fmolb.2022.955282