EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors

Hematopoietic stem cells (HSCs) and multipotent progenitors (MPPs) generate all cells of the blood system. Despite their multipotency, MPPs display poorly understood lineage bias. Here, we examine whether lineage-specifying transcription factors, such as the B-lineage determinant EBF1, regulate line...

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Detalles Bibliográficos
Autores principales: Lenaerts, Aurelie, Kucinski, Iwo, Deboutte, Ward, Derecka, Marta, Cauchy, Pierre, Manke, Thomas, Göttgens, Berthold, Grosschedl, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437269/
https://www.ncbi.nlm.nih.gov/pubmed/36048017
http://dx.doi.org/10.1084/jem.20212437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437269/
https://www.ncbi.nlm.nih.gov/pubmed/36048017
http://dx.doi.org/10.1084/jem.20212437

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