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Preparation of RNAs with non-canonical 5′ ends using novel di- and trinucleotide reagents for co-transcriptional capping

Many eukaryotic and some bacterial RNAs are modified at the 5′ end by the addition of cap structures. In addition to the classic 7-methylguanosine 5′ cap in eukaryotic mRNA, several non-canonical caps have recently been identified, including NAD-linked, FAD-linked, and UDP-glucose-linked RNAs. Howev...

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Detalles Bibliográficos
Autores principales: Depaix, Anaïs, Grudzien-Nogalska, Ewa, Fedorczyk, Bartlomiej, Kiledjian, Megerditch, Jemielity, Jacek, Kowalska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437278/
https://www.ncbi.nlm.nih.gov/pubmed/36060251
http://dx.doi.org/10.3389/fmolb.2022.854170