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Identification of key amino acid residues toward improving the catalytic activity and substrate specificity of plant-derived cytochrome P450 monooxygenases CYP716A subfamily enzyme for triterpenoid production in Saccharomyces cerevisiae

Triterpenoids constitute a group of specialized plant metabolites with wide structural diversity and high therapeutic value for human health. Cytochrome P450 monooxygenases (CYP) are a family of enzymes important for generating the structural diversity of triterpenoids by catalyzing the site-specifi...

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Detalles Bibliográficos
Autores principales: Romsuk, Jutapat, Yasumoto, Shuhei, Seki, Hikaru, Fukushima, Ery Odette, Muranaka, Toshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437279/
https://www.ncbi.nlm.nih.gov/pubmed/36061436
http://dx.doi.org/10.3389/fbioe.2022.955650