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Identification of key amino acid residues toward improving the catalytic activity and substrate specificity of plant-derived cytochrome P450 monooxygenases CYP716A subfamily enzyme for triterpenoid production in Saccharomyces cerevisiae
Triterpenoids constitute a group of specialized plant metabolites with wide structural diversity and high therapeutic value for human health. Cytochrome P450 monooxygenases (CYP) are a family of enzymes important for generating the structural diversity of triterpenoids by catalyzing the site-specifi...
Autores principales: | Romsuk, Jutapat, Yasumoto, Shuhei, Seki, Hikaru, Fukushima, Ery Odette, Muranaka, Toshiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437279/ https://www.ncbi.nlm.nih.gov/pubmed/36061436 http://dx.doi.org/10.3389/fbioe.2022.955650 |
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