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The crosstalk between MYC and mTORC1 during osteoclastogenesis

Osteoclasts are bone-resorbing cells that undergo extensive changes in morphology throughout their differentiation. Altered osteoclast differentiation and activity lead to changes in pathological bone resorption. The mammalian target of rapamycin (mTOR) is a kinase, and aberrant mTOR complex 1 (mTOR...

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Detalles Bibliográficos
Autores principales: Bae, Seyeon, Oh, Brian, Tsai, Jefferson, Park, Peter Sang Uk, Greenblatt, Matthew Blake, Giannopoulou, Eugenia G., Park-Min, Kyung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437285/
https://www.ncbi.nlm.nih.gov/pubmed/36060812
http://dx.doi.org/10.3389/fcell.2022.920683