Mitochondrial translocator protein deficiency exacerbates pathology in acute experimental ulcerative colitis

In human patients and animal models of ulcerative colitis (UC), upregulation of the mitochondrial translocator protein (TSPO) in the colon is consistent with inflammation. Although the molecular function for TSPO remains unclear, it has been investigated as a therapeutic target for ameliorating UC p...

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Detalles Bibliográficos
Autores principales: Jimenez, Isabel A., Stilin, Allison P., Morohaku, Kanako, Hussein, Mahmoud H., Koganti, Prasanthi P., Selvaraj, Vimal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437295/
https://www.ncbi.nlm.nih.gov/pubmed/36060674
http://dx.doi.org/10.3389/fphys.2022.896951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437295/
https://www.ncbi.nlm.nih.gov/pubmed/36060674
http://dx.doi.org/10.3389/fphys.2022.896951

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