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Tanshinone IIA reduces pyroptosis in rats with coronary microembolization by inhibiting the TLR4/MyD88/NF-κB/NLRP3 pathway

Pyroptosis is an inflammatory form of programmed cell death that is linked with invading intracellular pathogens. Cardiac pyroptosis has a significant role in coronary microembolization (CME), thus causing myocardial injury. Tanshinone IIA (Tan IIA) has powerful cardioprotective effects. Hence, this...

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Detalles Bibliográficos
Autores principales: Li, Hao-Liang, Tao-Li, Chen, Zhi-Qing, Li, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437365/
https://www.ncbi.nlm.nih.gov/pubmed/36039734
http://dx.doi.org/10.4196/kjpp.2022.26.5.335