Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner

Gastric cancer stem cells (GCSCs) are a major cause of radioresistance and chemoresistance in gastric cancer (GC). Therefore, targeting GCSCs is regarded as a powerful strategy for the effective treatment of GC. Atorvastatin is a widely prescribed cholesterol-lowering drug that inhibits 3-hydroxy-3-...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Ye Seul, Cho, Hee Jeong, Jung, Hye Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437372/
https://www.ncbi.nlm.nih.gov/pubmed/36039737
http://dx.doi.org/10.4196/kjpp.2022.26.5.367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437372/
https://www.ncbi.nlm.nih.gov/pubmed/36039737
http://dx.doi.org/10.4196/kjpp.2022.26.5.367

Ejemplares similares