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Identification of a phage-derived depolymerase specific for KL47 capsule of Klebsiella pneumoniae and its therapeutic potential in mice

Klebsiella pneumoniae is one of the major pathogens causing global multidrug-resistant infections. Therefore, strategies for preventing and controlling the infections are urgently needed. Phage depolymerase, often found in the tail fiber protein or the tail spike protein, is reported to have antibio...

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Detalles Bibliográficos
Autores principales: Li, Min, Wang, Hui, Chen, Long, Guo, Genglin, Li, Pei, Ma, Jiale, Chen, Rong, Du, Hong, Liu, Yuqing, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437526/
https://www.ncbi.nlm.nih.gov/pubmed/35513275
http://dx.doi.org/10.1016/j.virs.2022.04.005