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Identification of a phage-derived depolymerase specific for KL47 capsule of Klebsiella pneumoniae and its therapeutic potential in mice
Klebsiella pneumoniae is one of the major pathogens causing global multidrug-resistant infections. Therefore, strategies for preventing and controlling the infections are urgently needed. Phage depolymerase, often found in the tail fiber protein or the tail spike protein, is reported to have antibio...
Autores principales: | Li, Min, Wang, Hui, Chen, Long, Guo, Genglin, Li, Pei, Ma, Jiale, Chen, Rong, Du, Hong, Liu, Yuqing, Zhang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wuhan Institute of Virology, Chinese Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437526/ https://www.ncbi.nlm.nih.gov/pubmed/35513275 http://dx.doi.org/10.1016/j.virs.2022.04.005 |
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