Understanding the function of regulatory DNA interactions in the interpretation of non-coding GWAS variants

Genome-wide association studies (GWAS) have identified a vast number of variants associated with various complex human diseases and traits. However, most of these GWAS variants reside in non-coding regions producing no proteins, making the interpretation of these variants a daunting challenge. Prior...

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Detalles Bibliográficos
Autores principales: Zhong, Wujuan, Liu, Weifang, Chen, Jiawen, Sun, Quan, Hu, Ming, Li, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437546/
https://www.ncbi.nlm.nih.gov/pubmed/36060805
http://dx.doi.org/10.3389/fcell.2022.957292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437546/
https://www.ncbi.nlm.nih.gov/pubmed/36060805
http://dx.doi.org/10.3389/fcell.2022.957292

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