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Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism

Ecdysoneless (ECD) protein is essential for embryogenesis, cell-cycle progression, and cellular stress mitigation with an emerging role in mRNA biogenesis. We have previously shown that ECD protein as well as its mRNA are overexpressed in breast cancer and ECD overexpression predicts shorter surviva...

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Detalles Bibliográficos
Autores principales: Mohapatra, Bhopal C., Mirza, Sameer, Bele, Aditya, Gurumurthy, Channabasavaiah B., Raza, Mohsin, Saleem, Irfana, Storck, Matthew D., Sarkar, Aniruddha, Kollala, Sai Sundeep, Shukla, Surendra K., Southekal, Siddesh, Wagner, Kay-Uwe, Qiu, Fang, Lele, Subodh M., Alsaleem, Mansour A., Rakha, Emad A., Guda, Chittibabu, Singh, Pankaj K., Cardiff, Robert D., Band, Hamid, Band, Vimla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437571/
https://www.ncbi.nlm.nih.gov/pubmed/35675041
http://dx.doi.org/10.1158/1541-7786.MCR-22-0122