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Adeno-associated virus 9 vector-mediated cardiac-selective expression of human secretory leukocyte protease inhibitor attenuates myocardial ischemia/reperfusion injury

Protease enzymes contribute to the initiation of cardiac remodeling and heart failure after myocardial ischemic/reperfusion (I/R) injury. Protease inhibitors attenuate protease activity and limit left ventricular dysfunction and remodeling. Previous studies showed the cardioprotective effect of secr...

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Detalles Bibliográficos
Autores principales: Mongkolpathumrat, Podsawee, Nernpermpisooth, Nitirut, Kijtawornrat, Anusak, Pikwong, Faprathan, Chouyratchakarn, Wannapat, Yodsheewan, Rungrueang, Unajak, Sasimanas, Kumphune, Sarawut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437585/
https://www.ncbi.nlm.nih.gov/pubmed/36061560
http://dx.doi.org/10.3389/fcvm.2022.976083