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Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection

Hepatitis B virus (HBV) is a primary cause of chronic liver diseases in humans. HBV infection exhibits strict host and tissue tropism. HBV core promoter (Cp) drives transcription of pregenomic RNA (pgRNA) and plays a key role in the viral life cycle. Hepatocyte nuclear factor 4α (HNF4α) acts as a ma...

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Detalles Bibliográficos
Autores principales: Song, Yingying, Shou, Shuyu, Guo, Huimin, Gao, Zixiang, Liu, Nannan, Yang, Yang, Wang, Feifei, Deng, Qiang, Liu, Jing, Xie, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437612/
https://www.ncbi.nlm.nih.gov/pubmed/35568375
http://dx.doi.org/10.1016/j.virs.2022.05.002