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System level modeling and analysis of TNF-α mediated sphingolipid signaling pathway in neurological disorders for the prediction of therapeutic targets

Sphingomyelin (SM) belongs to a class of lipids termed sphingolipids. The disruption in the sphingomyelin signaling pathway is associated with various neurodegenerative disorders. TNF-α, a potent pro-inflammatory cytokine generated in response to various neurological disorders like Alzheimer’s disea...

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Detalles Bibliográficos
Autores principales: Banaras, Sanam, Paracha, Rehan Zafar, Nisar, Maryum, Arif, Ayesha, Ahmad, Jamil, Tariq Saeed, Muhammad, Mustansar, Zartasha, Shuja, Malik Nawaz, Paracha, Rizwan Nasir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437628/
https://www.ncbi.nlm.nih.gov/pubmed/36060699
http://dx.doi.org/10.3389/fphys.2022.872421