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Biased GPCR signaling by the native parathyroid hormone–related protein 1 to 141 relative to its N-terminal fragment 1 to 36

The parathyroid hormone (PTH)–related protein (PTHrP) is indispensable for the development of mammary glands, placental calcium ion transport, tooth eruption, bone formation and bone remodeling, and causes hypercalcemia in patients with malignancy. Although mature forms of PTHrP in the body consist...

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Detalles Bibliográficos
Autores principales: Peña, Karina A., White, Alex D., Savransky, Sofya, Castillo, Ignacio Portales, Jean-Alphonse, Frédéric G., Gardella, Thomas J., Sutkeviciute, Ieva, Vilardaga, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437850/
https://www.ncbi.nlm.nih.gov/pubmed/35933010
http://dx.doi.org/10.1016/j.jbc.2022.102332