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Biased GPCR signaling by the native parathyroid hormone–related protein 1 to 141 relative to its N-terminal fragment 1 to 36
The parathyroid hormone (PTH)–related protein (PTHrP) is indispensable for the development of mammary glands, placental calcium ion transport, tooth eruption, bone formation and bone remodeling, and causes hypercalcemia in patients with malignancy. Although mature forms of PTHrP in the body consist...
Autores principales: | Peña, Karina A., White, Alex D., Savransky, Sofya, Castillo, Ignacio Portales, Jean-Alphonse, Frédéric G., Gardella, Thomas J., Sutkeviciute, Ieva, Vilardaga, Jean-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437850/ https://www.ncbi.nlm.nih.gov/pubmed/35933010 http://dx.doi.org/10.1016/j.jbc.2022.102332 |
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