Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation

Protein degradation is fundamentally important to ensure cell homeostasis. In the endoplasmic reticulum (ER), the ER-associated degradation (ERAD) pathway targets incorrectly folded and unassembled proteins for turnover by the cytoplasmic proteasome. Previously, we showed that the rhomboid protease...

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Detalles Bibliográficos
Autores principales: Bock, Josephine, Kühnle, Nathalie, Knopf, Julia D., Landscheidt, Nina, Lee, Jin-Gu, Ye, Yihong, Lemberg, Marius K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437926/
https://www.ncbi.nlm.nih.gov/pubmed/35947953
http://dx.doi.org/10.1016/j.celrep.2022.111175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437926/
https://www.ncbi.nlm.nih.gov/pubmed/35947953
http://dx.doi.org/10.1016/j.celrep.2022.111175

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