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Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation
Protein degradation is fundamentally important to ensure cell homeostasis. In the endoplasmic reticulum (ER), the ER-associated degradation (ERAD) pathway targets incorrectly folded and unassembled proteins for turnover by the cytoplasmic proteasome. Previously, we showed that the rhomboid protease...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437926/ https://www.ncbi.nlm.nih.gov/pubmed/35947953 http://dx.doi.org/10.1016/j.celrep.2022.111175 |