IL1R2 increases regulatory T cell population in the tumor microenvironment by enhancing MHC-II expression on cancer-associated fibroblasts

BACKGROUND: Regulatory T cells (Treg) are an integral part of the tumor immune tolerance. Carcinoma-associated fibroblasts (CAFs) is a pivotal driver for accumulation of Treg cells in the tumor microenvironment (TME). The molecular nature underpinning Treg cells and CAFs coupling needs to be further...

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Detalles Bibliográficos
Autores principales: Chen, Lujun, Huang, Hao, Zheng, Xiao, Li, Yuan, Chen, Junjun, Tan, Bo, Liu, Yingting, Sun, Runzi, Xu, Bin, Yang, Min, Li, Bin, Wu, Changping, Lu, Binfeng, Jiang, Jingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438093/
http://dx.doi.org/10.1136/jitc-2022-004585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438093/
http://dx.doi.org/10.1136/jitc-2022-004585

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