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Caenorhabditis elegans NHR-14/HNF4α regulates DNA damage-induced apoptosis through cooperating with cep-1/p53

BACKGROUND: Nuclear hormone receptors are involved in transcriptional regulation and many important cellular processes including development and metabolism. However, its role in DNA damage-induced apoptosis remains elusive. METHODS: Synchronized young adult animals were irradiated with different dos...

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Detalles Bibliográficos
Autores principales: Sang, Lei, Dong, Rui, Liu, Rui, Hao, Qinggang, Bai, Weiyu, Sun, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438139/
https://www.ncbi.nlm.nih.gov/pubmed/36050770
http://dx.doi.org/10.1186/s12964-022-00920-5