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MIRTH: Metabolite Imputation via Rank-Transformation and Harmonization

Out of the thousands of metabolites in a given specimen, most metabolomics experiments measure only hundreds, with poor overlap across experimental platforms. Here, we describe Metabolite Imputation via Rank-Transformation and Harmonization (MIRTH), a method to impute unmeasured metabolite abundance...

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Detalles Bibliográficos
Autores principales: Freeman, Benjamin A., Jaro, Sophie, Park, Tricia, Keene, Sam, Tansey, Wesley, Reznik, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438248/
https://www.ncbi.nlm.nih.gov/pubmed/36050754
http://dx.doi.org/10.1186/s13059-022-02738-3