Stable expression of a truncated TLX variant drives differentiation of induced pluripotent stem cells into self-renewing neural stem cells for production of extracellular vesicles

BACKGROUND: Neural stem cells (NSCs)-derived extracellular vesicles (EVs) possess great potential in treating severe neurological and cerebrovascular diseases, as they carry the modulatory and regenerative ingredients of NSCs. Induced pluripotent stem cells (iPSCs)-derived NSCs culture represents a...

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Detalles Bibliográficos
Autores principales: Xu, Mingzhi, Chen, Gang, Dong, Yanan, Xiang, Shensi, Xue, Miaomiao, Liu, Yongxue, Song, Haijing, Song, Haifeng, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438273/
https://www.ncbi.nlm.nih.gov/pubmed/36056423
http://dx.doi.org/10.1186/s13287-022-03131-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438273/
https://www.ncbi.nlm.nih.gov/pubmed/36056423
http://dx.doi.org/10.1186/s13287-022-03131-4

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