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The novel role of ER protein TXNDC5 in the pathogenesis of organ fibrosis: mechanistic insights and therapeutic implications

Fibrosis-related disorders account for an enormous burden of disease-associated morbidity and mortality worldwide. Fibrosis is defined by excessive extracellular matrix deposition at fibrotic foci in the organ tissue following injury, resulting in abnormal architecture, impaired function and ultimat...

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Detalles Bibliográficos
Autores principales: Hung, Chen-Ting, Tsai, Yi-Wei, Wu, Yu-Shuo, Yeh, Chih-Fan, Yang, Kai-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438287/
https://www.ncbi.nlm.nih.gov/pubmed/36050716
http://dx.doi.org/10.1186/s12929-022-00850-x