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The novel role of ER protein TXNDC5 in the pathogenesis of organ fibrosis: mechanistic insights and therapeutic implications
Fibrosis-related disorders account for an enormous burden of disease-associated morbidity and mortality worldwide. Fibrosis is defined by excessive extracellular matrix deposition at fibrotic foci in the organ tissue following injury, resulting in abnormal architecture, impaired function and ultimat...
Autores principales: | Hung, Chen-Ting, Tsai, Yi-Wei, Wu, Yu-Shuo, Yeh, Chih-Fan, Yang, Kai-Chien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438287/ https://www.ncbi.nlm.nih.gov/pubmed/36050716 http://dx.doi.org/10.1186/s12929-022-00850-x |
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