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Temporal changes in cyclinD-CDK4/CDK6 and cyclinE-CDK2 pathways: implications for the mechanism of deficient decidualization in an immune-based mouse model of unexplained recurrent spontaneous abortion

BACKGROUND: Deficient endometrial decidualization has been associated with URSA. However, the underlying mechanism is poorly understood. This study aimed to investigate the temporal cytokine changes and the involvement of CyclinD-CDK4/6 and CyclinE-CDK2 pathways in the regulation of the G1 phase of...

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Detalles Bibliográficos
Autores principales: Chang, Zhuo, Kuang, Hai-xue, Zhou, Xueming, Zhu, Hui, Zhang, Yang, Fu, Yin, Fu, Qiang, Jiang, Bei, Wang, Wei, Jiang, Sha, Ren, Li, Ma, Lei, Pan, Xue, Feng, Xiao-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438304/
https://www.ncbi.nlm.nih.gov/pubmed/36050637
http://dx.doi.org/10.1186/s10020-022-00523-3