Retro-2 alters Golgi structure

Retro-2 directly interacts with an ER exit site protein, Sec16A, inhibiting ER exit of a Golgi tSNARE, Syntaxin5, which results in rapid re-distribution of Syntaxin5 to the ER. Recently, it was shown that SARS-CoV-2 infection disrupts the Golgi apparatus within 6–12 h, while its replication was effe...

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Detalles Bibliográficos
Autores principales: Yue, Xihua, Gim, Bopil, Zhu, Lianhui, Tan, Chuanting, Qian, Yi, Graham, Morven, Liu, Xinran, Lee, Intaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438350/
https://www.ncbi.nlm.nih.gov/pubmed/36056100
http://dx.doi.org/10.1038/s41598-022-19415-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438350/
https://www.ncbi.nlm.nih.gov/pubmed/36056100
http://dx.doi.org/10.1038/s41598-022-19415-x

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